Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression
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چکیده
منابع مشابه
Detection of gene expression and sequence analysis of chicken class II trans activator (CIITA)
BACKGROUND:Class II transactivator (CIITA) is a dominanttranscriptional element, controlling numerous genes in theimmune system. CIITA is expressed in a constitutive pattern inantigen presenting cells although its expression can occur inother cell types. Since the revelation of CIITA, there have beenconsiderable advances toward understanding its role as anactivator of MHC II genes in humans and...
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Background: The aim of present study is to asset the IL-2 promoter gene (SNP -475) as a candidate gene for multiple sclerosis (MS) susceptibility. Methods: This study included 70 patients with relapsing – remitting multiple sclerosis (RRMS) and 50 healthy controls. Following the extraction of genomic DNA from peripheral blood, frequency of genotypes and alleles of SNP -475 was calculated usi...
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ژورنال
عنوان ژورنال: Science
سال: 1986
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.3010456